The subway will be closed between St Clair West and Union stations on March 10 and 11.
Express shuttle buses will run along the route between Spadina and St Clair West stations.
St Clair West, Spadina, St George and Union stations will remain open for fare sales and buses and streetcars.
Dupont, Museum, Queen’s Park, St Patrick, Osgoode and St Andrew will be closed.
Wheel-Trans service will be available. To request service, customers can speak with TTC staff at any location throughout the closure.